Endocrine Abstracts

Objective: In this study we analysed the prediabetes incidence in women with polycystic ovary syndrome (PCOS), as well as prediabetes and cardiovascular disease (CVD) risk factors in women with PCOS.Methods: This study included 148 women with PCOS, with no type 2 diabetes mellitus (T2DM) and CVD present at the baseline. We determined a comprehensive panel of biochemical parameters, including lipid profile, glucose and insulin levels during oral glucose t...

Three phenotypes of prediabetes are known: impaired fasting glucose (IFG), Impaired glucose tolerance (IGT), and combined IFG/IGT. IFG is associated with impaired early phase and normal second-phase of insulin secretion. IGT is associated with both impaired early and late phase of insulin secretion. Numerous studies have demonstrated efficacy of lifestyle intervention in improving 2-hr oral glucose tolerance and fasting plasma glucose (FPG) in individuals with prediabetes, whi...